矽肺高危人群二种资料早期判别的比较

Early discriminant analysis for high risk group of silicosis based on their job data

目的 矽肺高危人群的早期判别。方法 １０３ 例Ⅰ期矽肺患者和１４９ 例０ ＋ 期接尘工人， 均记录接尘浓度、接尘工龄等８ 个环境因素指标， 也均采取二者的枕后部头发０－５ 克， 作Ｚｎ 、Ｃｕ 、Ｓｅ 、Ｎｉ、Ｆｅ 、Ｍｎ 、Ｍｇ 、Ｃａ 等８ 种微量元素的测定， 用ＳＡＳ 软件中的非参数判别法判别。结果 经现场验证， 得出微量元素的判别优于环境因素的判别， 二种判别经卡方检验（χ２ ＝ ２－１２０ ２） 无显著性差异。结论 用Ⅰ期矽肺病人作标准， 测定发中微量元素， 预测０ ＋ 期中的高危人群是切实可行。

Objective To make early discriminant analysis for high risk group of silicosis.Methods Eight environmental factors,such as dust concentrations,length of exposure to it,etc.were recorded for 103 patients with silicosis stage I and 149 dust exposed workers at silicosis stage 0 +,and their back occipital hair specimens were collected and determined for contents of eight trace elements,such as copper,selenium,nickel,iron,manganese,calcium,etc.Non parametric discriminant analysis was used to distinguish the high risk group of silicosis with SAS software.Results Discriminant analysis with trace element contents was better than that with environmental factors,but no statistical significance was reached,with χ 2 of 2 120 2,P>0 05.Conclusion Determination of trace element contents in the hair specimens of dust exposed workers to predict high risk of silicosis at stage 0 + is practicable,as compared with those in the patients of silicosis.