摘要
本文对３０例血管性痴呆（ＶＤ）患者针灸、中药治疗前后血浆ＴＸＢ_２、６－ｋｅｔｏ－ＰＧＦ_(１α)含量进行检测，并与同龄健康人做对照。结果发现 ＶＤ患者血浆 ＴＸＢ_２含量明显升高，６－ｋｅｔｏ－ＰＧＦ_(１α)含量明显下降，与对照组比较差异有显著意义（Ｐ＜０．０１）。提示 ＶＤ患者此二者含量严重失衡。经针灸、中药治疗后能明显升高ＶＤ患者血浆６－ｋｅｔｏ－ＰＧＦ_(１α)含量，降低ＴＸＢ２含量，这种作用与临床疗效呈正相关。认为针灸、中药能调整ＶＤ患者血浆ＴＸＢ_２、６－ｋｅｔｏ－ＰＧＦ_(１α)之间的平衡，增加患者脑血流量，提高脑代谢率，改善脑功能。这可能是针药治疗ＶＤ取效的主要机制之一。
In the present paper, changes of TXB2, 6-keto-PGF1α. contents before and after treatment by acupuncture, moxibustion and Chinese medicinal herbs in 30 vascular dementia(VD) patients were observed and compared with the normal values of healthy people. Results showed that in VD patients, the content of serum TXB2 increased significantly and that of 6-keto-PGF1α decreased markedly in comparison with control group (P < 0. 01 ), suggesting a significant imbalance between plasma TXB2 and 6-keto-PGF1α;after combined treatment of acupuncture, moxibustion and Chinese herbs, the content of plasma 6-keto-PGF1α was raised remarkably and that of TXB2 lowered, which had a positive correlation with clinical therapeutic effect. The fact indicates that this combined treatment is capable of regulating the balance between plasma TXB2 and 6-keto-PGF1α, increasing cerebral blood flow, raising the metabolic rate of the brain tissues and improving functions of the brain.
出处
《针刺研究》
CAS
CSCD
1999年第4期245-248,共4页
Acupuncture Research
