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hCTR1及其在子宫颈鳞癌中表达的临床意义 被引量：2

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摘要 人类铜转运蛋白(hum an copper transporter 1,hCTR1)被认为是人体内具有高亲和力的铜摄入蛋白。国外学者研究发现铜与肿瘤细胞密切相关,很多类型的肿瘤患者的血清中含有异常高水平的铜,hCTR1也调节细胞中顺铂的含量。hCTR1在子宫颈鳞癌中的表达情况有望成为子宫颈鳞癌患者治疗的新的有效生物靶点。本文主要对hCTR1及其在子宫颈鳞癌中的表达状况及其在治疗中的意义进行综述。
作者 刘洪博 何春年 张清泉 贾斌 邱雷 张晓娟 李聪 杜红丽
机构地区 河北哈励逊国际和平医院病理科 河北省人民医院病理科
出处 《临床与实验病理学杂志》 CAS CSCD 北大核心 2011年第8期882-884,共3页 Chinese Journal of Clinical and Experimental Pathology
关键词 人类铜转运蛋白 子宫颈肿瘤 顺铂 组织芯片技术 免疫组织化学
分类号 R737.33 [医药卫生—肿瘤]
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参考文献24

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同被引文献19

  • 1辛海,耿明,陈诵芬,陈秀芳,徐增祥.宫颈癌及其癌前病变组织中p16^(INK4a)和PCNA的表达及临床意义[J].中华肿瘤防治杂志,2007,14(20):1563-1567. 被引量：12
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临床与实验病理学杂志
2011年 第8期

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