摘要
目的:探讨应用单腔起搏器治疗血管迷走性晕厥(VVS)的效果。方法:将确诊为VVS的患者42例,随机分为起搏器组(22例)和药物治疗组(20例)进行疗效对照。起搏器组置入单腔起搏器(VVI 10例,VVIR12例),药物治疗组口服美托洛尔治疗。2组患者出院后6个月均复查直立倾斜试验并随访,观察对晕厥的预防效果。结果:起搏器组直立倾斜试验阴转率82.0%,无一例发生晕厥,2例仍有晕厥先兆,但症状明显减轻;药物治疗组直立倾斜试验阴转率50.0%,8例发生晕厥,但发作次数减少。2组直立倾斜试验阴转率和晕厥发生率比较,差异均有统计学意义(P<0.01)。结论:对于反复发作的VVS患者,安装起搏器可以有效防止晕厥的发生,药物治疗亦有一定疗效,但不能完全防止晕厥的发生。
Objective:To investigate the effect of VVI/VVIR pacing on vasovagal syncope(VVS). Method:Forty-two patients diagnosed as VVS by tilt tble test(TTT) in Wuhan Puai Hospital were selected into the study.They were divided into two groups randomly: group with pacemaker(22) and group with drugs(20).Tilt tble test was examined again after six months and follow-up. Result:The rate of TTT from positive to negative was 82% in group with pacemaker,50% in group with drugs.The two groups had a statistical difference(P0.01).All the 22 patients with pacemaker implantation were free from syncope,in which 2 still had per-syncope discomfortness,but the syncope onset was slightly.Twelve cases relapse of syncope in the groups with drugs during the follow-up period.The two groups also had a statistical difference(P0.01). Conclusion:In the VVS patients with recurrent syncope,VVI/VVIR pacing could prevent from syncope efficiently.Drug therapy also was effective,but syncope can not be prevented.
出处
《临床心血管病杂志》
CAS
CSCD
北大核心
2011年第8期612-613,共2页
Journal of Clinical Cardiology