摘要
目的探讨应用Z值(Z-score)诊断绝经前妇女和小于50岁男性股骨近端骨质疏松症(Osteoporosis,OP)的意义。方法在北京城区2744例正常人群中选择受检者,以股骨近端为测量点进行骨密度(Bone mineral density,BMD)测量观察在受试者中应用Z值对OP的诊断意义并与T值诊断OP的患病率比较。结果受试者应用Z值诊断OP患病率较应用T值诊断明显降低,但男性在50岁以后出现患病率加速趋势。结论应用Z值诊断绝经前妇女和小于50岁男性股骨近端OP可以避免过早的诊断OP,但其与骨折风险的相关性将有待于进一步研究。
Objective Aim To explore the diagnostic significance of Z score in proximal femur osteoporosis to pre-menopause women and men younger than 50 years old.Methods Proximal femur was chosen to determine bone mineral density in the cohort of 2744 normal residents in urban area.Z score was obtained and compared with T value in the subjects.Results The incidence rate of osteoporosis diagnosed by Z score was significantly lower than those by T value.However,the incidence becomes increasing for men older than 50 years old.Conclusion Application of Z score for diagnosis of osteoporosis to pre-menopause women and men before 50 could reduce misdiagnosis of osteoporosis at early age,but the relationship to the risk of fracture remains to be determined.
出处
《中国医疗设备》
2011年第8期114-117,共4页
China Medical Devices