琥珀胆碱引起的血钾升高、肌颤和肌痛三者之间的相关性研究

Correlative Study Among the Suxametbonium-induced Increase of Serum Potassium,Muscle Fasciculation and Postoperative Myalgia

选择ASAⅠ～Ⅱ级胸或腹部手术的患者60例,分别于诱导前和气管插管后抽取静脉血测定血钾浓度,并观察患者诱导期间有无肌纤维成束收缩(肌颤),术后1～3天询问患者有无肌痛.结果患者气管插管后的血钾浓度显著上升(P<0.05),肌颤和肌痛的发生率分别为75.0%和62.5%.气管插管后血钾浓度与肌颤和肌痛均呈正相关,肌颤和肌痛也呈正相关(P<0.01).

Sixty patients with ASA Ⅰ～Ⅱ were collected to determine the serum potassium in the blood samples taken from a vein before induction and intubation and after intubation. Fasciculations were observed during induction and the patients were questioned about myalgia 1-3 days after the surgery. The serum potassium was significantly increased by 3.4% after induction (P<0. 05). The incidence of muscle fasciculation and postoperative myalgia was 75.0% and 62.5% respectively. There was a significantly positive correlation between the serum potassium after intubation and muscle fasciculation,myalgia,and between muscle fasciculation and myalgia (P<0. 01).