摘要
目的:研究蜂针疗法对类风湿关节炎(RA)所致膝关节滑膜炎的临床疗效。方法:选取获得随访的RA合并膝关节滑膜炎患者46例。随机分为蜂针组和对照组。对照组采用MTX、SASP和美洛昔康片口服。蜂针组在对照组的基础上加用蜂针疗法,三个月为一疗程。治疗前后观察Lequesne指数、VAS、HSS评分和膝周长、B超积液和滑膜厚度探查、ESR、CRP检测。结果:蜂针组临床疗效优于对照组(P<0.05)。与对照组比较,蜂针组治疗1月、3月后Lequesne指数、VAS评分明显降低,HSS评分明显升高(P<0.05);膝周长和积液深度均明显减少。蜂针组、对照组与治疗前比较,1月、3月后Lequesne指数、VAS评分明显降低,HSS评分明显升高(P<0.05、P<0.01)。膝周长和积液深度、滑膜厚度均明显减轻(P<0.05、P<0.01)。结论:两组治疗RA所致膝滑膜炎均有较好的临床效果,但蜂针组见效早、疗效更为显著。
Objective:To study the clinical effect of bee-sting(venom)therapy to the knee synovitis caused by Rheumatoid Arthritis(RA).Methods: forty-six RA combine with knee synovitis patients randomly divided into bee-venom group and medicine group,with 23 cases in each.Patients of medicine group were treated with oral administration of Methotrexate(MTX),SASP and Meloxicam;and patients of bee-venom group were treated with Bee-sting on the basis of the above-mentioned Western medicines.The treatment lasted for 3 months.Observed the Lequesne index,VAS,HSS score,knee circumference,B–ultrasonic effusion,synovial thickness,ESR and CRP results before and after treatment.Results:Comparison between two groups showed that the clinical effect of bee-venom group is better than medicine group(P0.05).Compared with medicine group,after 1 month and 3 months' treatment the Lequesne index,VAS score are obvious lower for bee-venom group,and also the HSS score is obvious higher(P0.05),and the knee circumference and effusion depth are all reduced.Compared with pre-treatment,after 1 month and 3 months' treatment for both bee-venom group and medicine group,the Lequesne index,VAS score are both obvious lower,and the HSS score is obvious higher(P0.05,P0.01) too.The knee circumference,effusion depth and synovial thickness are also reduced(P0.05,P0.01).Conclusion:Both of the above-mentioned treatments have good clinical effect to the knee synovitis caused by RA,but the bee-venom therapy have earlier and more significant effect than simply use medication.
出处
《中华中医药学刊》
CAS
2011年第8期1904-1906,共3页
Chinese Archives of Traditional Chinese Medicine
关键词
蜂针
类风湿关节炎
滑膜炎
Bee-sting
Rheumatoid arthritis
knee Synovitis