自拟固胃汤减轻胃癌术后化疗不良反应的临床观察

The Clinical Observation of Guwei Tang for Treating Adverse Effect Induced by Chemotherapy of Gastric Cancer Surgery

目的:观察固胃汤减轻胃癌术后化疗所致不良反应的临床疗效。方法:治疗组31例化疗开始时同时口服固胃汤,直至术后辅助化疗全部结束后停用;对照组29例,根据化疗过程中出现的不良反应给予对症处理来减轻症状。结果:治疗组消化道反应、全身症状的发生频率较对照组显著降低(P<0.05),对血液系统毒性起到了减轻的作用(P<0.05),同时,中药能明显提高患者生存治量。结论:固胃汤能明显减轻化疗药物的不良反应,使患者获得更多的治疗机会,提高生存率。

Objective：To observe the therapeutic of Guwei Tang for treating adverse effects induced by chemotherapy for gastric cancer surgery.Methods： The treatment group including 31 cases were treated orally Guwei Tang as begining of chemothrapy and finished after all chemothrapy.While the control group including 29 cases were treated with symptomatic treatment to alleviate adverse reaction when it appeared in course of chemothrapy.Resluts： The incidence of adverse reaction of alimentary canal and general symptoms were cut down markedly（P0.05） and the toxicity of hematological system was lessened obviously（P0.05）in the treatment group.The KPS score was improved apparently in the treatment group.Conclusion： Guwei Tang could alleviate adverse reaction of chemotherapy markedly and that made patient get more chemotherapy medicine opportunity,raise survival rate.