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结核分枝杆菌分泌蛋白TB10.4的功能和应用 被引量：2

Function and application of the secrete proteins TB10.4 in Mycobacterium tuberculosis
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摘要 近年来,结核的发病率又呈上升趋势,传统的结核疫苗已无法起到有效的保护作用。结核分枝杆菌分泌蛋白由于具有良好的免疫保护性因而备受关注。结核分泌蛋白TB10.4是免疫主导的蛋白,能够激发有效的免疫反应,因而成为研究结核新疫苗靶抗原之一。本文就近几年结核分枝杆菌TB10.4的相关研究作一综述。 In recent years,the morbidity of Tuberculosis increases obviously,but the traditional vaccine can’t provide effective protection.The secrete proteins of Mycobacterium tuberculosis have been given more attention because of its good immune response.TB10.4,which is a immunodominant antigen,becomes one of the target antigens for studies on tuberculosis vaccine considering that it can induce effective immune response.This review presents the related research progress of TB10.4 of Mycobacterium tuberculosis.
作者 王瑞博 井申荣
机构地区 昆明理工大学生命科学与技术学院
出处 《生命的化学》 CAS CSCD 北大核心 2011年第4期598-600,共3页 Chemistry of Life
基金 云南省应用基础研究项目(2007C032M) 国家自然科学基金项目(30872398) 863计划重大项目(2006AA02A227)资助
关键词 结核分枝杆菌 卡介苗 TB10.4 Mycobacterium tuberculosis BCG TB10.4
分类号 R378 [医药卫生—病原生物学]
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共引文献5

同被引文献45

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生命的化学
2011年 第4期

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