益生菌在肥胖及其代谢综合症中的潜在作用

Potenial function of probiotics in obesity and associated metabolic disorder

肥胖以及相关的代谢综合症已经成为全球性的公共健康问题。大量的研究表明,肥胖形成以及减肥过程均与肠道菌群密切相关且相互影响。肠道菌群以及弱炎症反应成为肥胖以及相关代谢综合症的两大重要影响因素。文章综述了近几年来,肠道菌群失调对宿主能量储存以及新陈代谢的影响,以及弱炎症反应对肥胖引起的代谢综合症的影响。大量的研究证明,益生菌可以调节肠道菌群以及改善肠道内弱炎症反应,借助于益生菌方法也许能为由肠道菌群失调以及弱炎症反应引起的肥胖及其代谢综合症提供一种新的方法。

Obesity and the associated metabolic disorder have been the worldwide public healthy problems.The development of obesity and the process of losing weight are associated with the intestine microbiota.Recent literatures indicate that the intestine microbiota dysbiosis and the low grade inflamationary have been two main factors affect the development of obestiy and the related metabolic disorder.The present review focused on recent studies on how intestine microbiota affected host metabolism and energy storage.It also reviewed the interplay between obesity,intestine microbiota,low grade inflamationary.Considering the functions of the probiotics,probiotics approach appeared as a potential interesting treatment to control the obesity linked to gut microbiota dysbiosis and the metabolic disorder related to obesity.