CTn-T联合NT-proBNP对急性心肌梗死的诊断价值研究

Study on the value of CTn-T combined with NT-proBNP on the early diagnosis of acute myocardial infarction

目的评价肌钙蛋白T(CTn-T)和N末端B型钠尿肽原(NT-proBNP)对急性心肌梗死(AMI)的早期诊断价值。方法 AMI患者50例作为AMI组,30例健康检查者作为对照组,对照组抽清晨空腹肘静脉血3ml用于CTn-T和NT-proBNP检测,AMI组于入院后即刻抽肘静脉血3ml,置于肝素抗凝管后送检。结果 AMI组CTn-T和NT-proBNP均高于对照组,差异有统计学意义(P<0.05)。CTn-T诊断界值为0.35ng/ml,NT-proBNP诊断界值为0.45ng/ml。CTn-T联合NT-proBNP检查时,对AMI的诊断敏感性和特异性均明显优于单项检查。结论 CTn-T和NT-proBNP联合检测对AMI的早期诊断具有较好的敏感性和特异性,值得临床推广。

Objective To evaluate the diagnostic value of CTn-T combined with NT-proBNP on the early acute myocardial infarction（AMI）.Methods 50 patients with AMI were grouped into AMI group,30 healthy physical examinees served as control group.Collected 3ml Fasting vein blood of the elbow of the control group in the early morning for the detection of CTn-T and NT-proBNP.And collected 3ml Fasting vein blood of the elbow of the AMI group at once after hospitalization,and then placed the blood in a test tube with low molecular heparin and submitted for inspection.Results The CTn-T and NT-proBNP of the AMI group were respectively higher than those of the control group in the early stage,and the differences were statistically significant （P0.05）.The sensitivity and specificity of CTn-T combined with NT-proBNP on the early diagnosis of AMI was better than each other alone.Conclusion The sensitivity and specificity of CTn-T combined with NT-proBNP on the early diagnosis of ami was well,which is worth clinical popularizing.