原发性高血压患者出生时体质量与肾脏体积、体质量指数的相关性研究

Relative study of birth weight,kidney volume and BMI in primary hypertension

目的研究原发性高血压患者出生时体质量与肾脏体积、体质量指数的相关性。方法原发性高血压患者63例作为高血压组,血压正常的健康体检者34例作为对照组,测量2组血压、肾脏体积,计算体质量指数,询问出生时体质量。结果高血压组收缩压、舒张压、BMI、低出生体质量发生率均高于对照组,出生时体质量低于对照组,差异均有统计学意义(P<0.01和P<0.05)。但经体表面积校正肾脏体积2组比较差异无统计学意义(P>0.05)。结论出生时体质量影响成年时高血压的形成,但不是通过减少肾脏体积介导的,BMI是高血压的危险因素。

Objective To study the relationship between birth weight,kidney volume and BMI in primary hypertension.Methods 63 patients with primary hypertension were regarded as hypertension group,and 34 healthy controls with normal blood pressure were regarded as control group.Blood pressure and kidney volume were measured,body mass index was calculated,and birth body weight was asked.Results In hypertension group,systolic hypertension,diastolic blood pressure,BMI,and the incidence rate of low birth weight was higher than those in the control group,but birth weight was lower than that in the control group,and the differences were statistically significant（P0.01 and P0.05）.Surface area correction of renal size showed that there was no significant difference between the two groups（P0.05）.Conclusion Birth weight can affect the formation of adult hypertension not by reducing the size of the kidney-mediated,and BMI is a risk factor for hypertension.