欣母沛预防高危妊娠产后出血的临床疗效观察

Clinical Study on Preventing Postpartum Hemorrhage in High Risk Pregnancy Women by Hemabate

目的观察欣母沛用于预防高危妊娠产后出血的临床疗效。方法选择80例有宫缩乏力性产后出血高危因素的产妇,随机分为实验组和对照组,比较两组术中、产后2 h及24 h出血量。实验组在胎儿娩出后宫体注射欣母沛250μg,对照组于胎儿娩出后宫体注射催产素20 U,同时静脉滴注催产素20 U。结果实验组比对照组术中、产后2 h及产后24 h平均出血量减少,差异均有统计学意义(P<0.05)。结论欣母沛用于高危妊娠产后出血安全有效,值得临床推广。

Objective To observe preventive effect of Hemabate for postpartum hemorrhage in high risk pregnant women. Methods 80 high risk pregnant women were divided randomly into two groups： experimental group and control group. The experimental group was given Hemabate 25 μg into uterine muscle after delivery of the fetus, while for the control group, oxytocin 20 U was injected into uterine muscle immediately after delivery of the fetus and 20 U into vein. The amount of bleeding during operation, 2 hours and 24 hours after delivery for the two groups was measured. Results The amount of bleeding during operation, 2 hours and 24 hours after delivery in experimental group was much less than that in control group. Conclusion Hemabate is more effective in reduction and prevention of postpartum hemorrhage. It is convenient, safe and quick.