联合检测CTnI、MB和心肌酶学在评价心肌损伤中的应用

目的探讨人血中心肌肌钙蛋白I（CTnI）、肌红蛋白（MB）和心肌酶学在心肌损伤中的临床意义。方法对80例急性冠状动脉综合征（ACS）患者血清中CTnI、MB和肌酸激酶同工酶（CK—MB）进行联合检测，CTnI、MB采用化学发光法，CK—MB采用日本OLYMPUS—AU400全自动生化分析仪。结果在检测的80例ACS患者血清中CTnI增高66例，MB增高46例，CK—MB增高42例，而健康体检组三项检测均正常。结论联合检测CTnI、MB、CK—MB水平，可提高ACS诊断率。

Objective To explore the clinical significance of combined measurement of cardiac troponin I （CTnI） , Myoglobin （MB） and cardiac enzymes for evaluating myocardial damage. Methods To do the combined detection of the CTnI MB and cardiac enzymes in 80 acute coronary syndrome （ ACS ） patients＇ serum. Results Among the serums of the 80 acute coronary syndrome （ ACS ） patients whom were detected, the CTnI of 66 patients increased; the MB of 46 patients increased; the CK - MB of 42 patients increased; while the three testing results turned to be normal among those in the physical exam group. Conclusion The diagnostic rate of acute coronary syndrome （ ACS ） is greatly improved through the joint detection of the quality determination of MB, CK - MB and CTnI.