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Cyclin G_2调节细胞增殖周期的研究进展

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摘要 细胞周期素G2(CyclinG2)是一个较新发现的细胞周期素,其基因定位于染色体5q32-34,其cDNA长约8.60kb.其与CyclinG1、CyclinI同属于CyclinG亚类。CyclinG2可能不同于其它周期素,其表达可被DNA损伤和抑癌基因VHL诱导,对细胞增殖可能起负性调节作用。实验表明CyclinG2可通过与PP2A形成复合物、影响细胞骨架等途径来调节细胞周期。本文将针对CyclinG2调节细胞周期的研究进展作一综述。
机构地区 中国医科大学
出处 《中国医药指南》 2011年第23期219-220,共2页 Guide of China Medicine
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参考文献4

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