中西医结合三联法整体治疗慢性重型肝炎191例疗效观察

Effect of Integrative Chinese and Western Medicine on 191 Patients with Chronic Severe Hepatitis

目的:用中西医结合三联法整体治疗慢性重型肝炎,观察其疗效。方法:191例患者均采用中西医结合三联法治疗,即在西医支持及对症治疗的基础上,以院内中药制剂整体施治,以降酶退黄、调节免疫功能、调整蛋白比值、缓解门脉高压、软肝缩脾、利水、止血等,同时针对临床上的突出矛盾如昏迷、高黄疸、肾衰、顽固性胸腹水等,配合中药汤剂口服或灌肠辨证施治,多途径给药、多靶点治疗。结果:19l例患者中,显效35例,有效110例,无效46例,总有效率75.9%。早期疗效明显好于中晚期。结论:中西医结合治疗在提高慢性重型肝炎的有效率及降低病死率方面具有明确优势,精选重型肝炎的中西医结合治疗方案,有着重要的临床意义和应用前景。

Objective：To observe effect of integrative Chinese and western medicine on 191 patients with chronic severe hepatitis.Methods：In addition to symptomatic treatment,the 191 patients were given Chinese medicine dispensed in our hospital.The dispensed medicine aimed to lower enzyme,regulate immune system,regulate protein ratio,relieve portal hypertension,ameliorate liver and spleen,drain water and stop bleeding.Besides,Chinese decoction or enema were used so as to check comma,jaundice,renal failure,Stubborn angiographic water.Results：Of 191 patients,35 patients responded significantly,110 patients responded favorably,46 patients not responded,total effective rate reached 75.9%.Conclusion：Integrative Chinese and western Medicine has definite curative effects and can lower mortality rate.Selected integrative treatment regimen will have clinical significance and wide application prospect.