左氧氟沙星治疗47例合并肝损害肺结核患者疗效分析

The effect of levofloxacin on pulmonery tuberculosis patients with liver injury

目的:分析左氧氟沙星治疗合并肝脏损害的肺结核患者临床疗效及安全性。方法:回顾性分析我院收治的合并肝损害的肺结核患者47例,予以左氧氟沙星为主的联合化疗,并给予适当保肝治疗,进行疗效及安全性分析。结果:治疗9月后显效30例,有效15例,无效2例,总有效的率95.7%,肝脏损害未进一步加重。结论:左氧氟沙星联合抗结核药物治疗伴肝功能损害的肺结核疗效显著,肝毒性小,值得临床进一步研究。

Objective： To evaluate the effect of levofloxacin on pulmonery tuberculosis patients with live injury. Methods： Ret- rospective analysist the effect and safety of levofloxacin on 47 pulmonery tuberculosis patients with live injury. Result： After 9 months of treatment, 30cases showed effective , 15cases were valid , and 2 cases were inefficient , and total effective rate was 95.7%, and the liver injury was not deteriorative. Conclusion： It was siganificant effect of levofloxacin combined with routine chemical therapy on pulmonery tuberculosis patients with live injury, and ill effect little , worth to further clinical investigation.