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Advances in genomic selection in domestic animals 被引量:8

Advances in genomic selection in domestic animals
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摘要 Genomic selection (GS) is a marker-assisted selection method, in which high density markers covering the whole genome are used simultaneously for individual genetic evaluation via genomic estimated breeding values (GEBVs). GS can increase the accuracy of selection, shorten the generation interval by selecting individuals at the early stage of life, and accelerate genetic progress. With the availability of high density whole genome SNP (single nucleotide polymorphism) chips for livestock, GS is reshaping the conventional animal breeding systems. In many countries, GS is becoming the major genetic evaluation method for bull selection in dairy cattle and GS may soon completely replace the traditional genetic evaluation system. In recent years, GS has become an important research topic in animal, plant and aquiculture breeding and many exciting results have been reported. In this paper, the methods for obtaining GEBVs, factors affecting the accuracy of GEBVs, and the current status of implementation of GS in livestock are reviewed. Some unresolved issues related to GS in livestock are also discussed. Genomic selection (GS) is a marker-assisted selection method, in which high density markers covering the whole genome are used simultaneously for individual genetic evaluation via genomic estimated breeding values (GEBVs). GS can increase the ac- curacy of selection, shorten the generation interval by selecting individuals at the early stage of life, and accelerate genetic pro- gress. With the availability of high density whole genome SNP (single nucleotide polymorphism) chips for livestock, GS is re- shaping the conventional animal breeding systems. In many countries, GS is becoming the major genetic evaluation method for bull selection in dairy cattle and GS may soon completely replace the traditional genetic evaluation system. In recent years, GS has become an important research topic in animal, plant and aquiculture breeding and many exciting results have been reported. In this paper, the methods for obtaining GEBVs, factors affecting the accuracy of GEBVs, and the current status of implementation of GS in livestock are reviewed. Some unresolved issues related to GS in livestock are also discussed.
出处 《Chinese Science Bulletin》 SCIE EI CAS 2011年第25期2655-2663,共9页
基金 supported by the National '948' Project (2011-G2A,2010-C14) the Key Development of New Transgenic Breeds Project (2009ZX08009-146B) the National Natural Science Foundation of China (30800776) the Innovation Fund for Graduate Student of China Agricultural University
关键词 全基因组 家养动物 标记辅助选择 单核苷酸多态性 育种值估计 遗传评价 世代间隔 早期阶段 genomic selection (GS), genomic estimated breeding value (GEBV), marker-assisted selection (MAS), domestic animals,breeding
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