增强CT定量分析在骶骨骨巨细胞瘤诊断中的应用价值

Value of quantitative analysis of enhanced CT scan in the diagnosis of giant cell tumor of sacral bone

目的探讨骶骨骨巨细胞瘤的CT增强扫描特点及其在诊断中的应用价值。方法回顾分析60例骶骨肿瘤患者的CT增强扫描特点,依据病理结果,划分骨巨细胞瘤(实验组)与非骨巨细胞瘤(对照组)进行统计学分析,定量研究CT增强扫描后CT值的变化特征。结果在60例骶骨肿瘤中,骨巨细胞瘤22例,增强后强化最显著区域平均CT值为121.59±21.82HU;非骨巨细胞瘤38例,增强后强化最显著区域平均CT值为61.24±20.60HU;二者之间差异显著(P<0.05)。ROC曲线分析表明,当CT值≥97HU时,诊断骨巨细胞瘤的敏感度为90.9%,特异性为99.97%。结论 CT增强扫描,CT值的定量分析在骶骨骨巨细胞瘤的定性诊断中有一定的导向价值。

Objective To investigate the characteristics and the value of enhanced CT scan in the diagnosis of giant cell tumor of sacral bone. Methods A retrospective analysis was performed in results of enhanced CT scan of sixty patients with sacral tumor. All patients were divided into two groups： giant cell tumor group according to the pathological diagnosis （n=22） and non-giant cell tumor group （n=38）. All patients were examined with enhanced CT scan and the CT values were analyzed quantitatively. Results In giant cell tumor group, the average CT value of the most significant regions was 121.59±21.82HU. In non-giant cell tumor group, the average CT value was 61.24±20.60HU. There was a significant difference between the two groups （P〈0.05）. The analysis of ROC curve showed that： if CT value ≥ 97HU, the sensitivity rate and specificity rate on the diagnosis of giant cell tumor of sacral bone were 90.9% and 99.97% respectively. Conclusions Enhanced CT scan has some value in the diagnosis of giant cell tumor of sacral bone.