胺碘酮与普罗帕酮治疗阵发性室上性心动过速的临床研究

Clinical Research of Amiodarone and Propafenone Treated in Patient with Paroxysmal Superventricular Tachycardia

目的:探讨胺碘酮与普罗帕酮治疗阵发性室上性心动过速的临床疗效。方法:将2007年1月至2010年12月收治的阵发性室上性心动过速62例随机分为胺碘酮组和普罗帕酮组各31例,分别应用胺碘酮和普罗帕酮治疗,比较两组的临床疗效。结果:胺碘酮组和普罗帕酮组的总有效率分别为903%(28/31)和83.9%(26/31),差异无统计学意义(P>0.05)。结论:胺碘酮与普罗帕酮治疗阵发性室上性心动过速均可取得较好的临床疗效,但胺碘酮更好。

Objective： To explore the clinical efficacy of Amiodarone and Propafenone treated in patient with paroxysmal superventrieular tachyeardia （PSVT）. Method： 62 patients with PSVT were divided into Amiodarone group and Propafenone group randomly from Jan.2007 to Dec 2010, and each group was 31 cases. The patients in Amiodarone group and Propafenone group were treated by Amiodarone and Propafenone respectively. The clinical effect was compared between the two groups. Results： The total effective rate in Amiodarone group and Propafenone group was 90.3%（28/31 ）and 83.9%（26/31 ）respectively, and there was not significantly difference between the two groups （P 〉 0.05）. Conclusions： There are good clinical effective of both Amiodarone and Propafenone treated in patient with PSVT, but Amiodarone is better than Propafenone.