女性抑郁症患者血清甲状腺激素水平研究

Study of serum thyroid hormone levels of female patients with depression

目的:探讨女性血清甲状腺激素水平与抑郁症的关系。方法:采用免疫化学发光法对58例女性抑郁症患者及对照组40例健康女性的血清游离三碘甲状腺原氨酸(FT3),游离甲状腺素(FT4),促甲状腺素(TSH)进行了检测。结果:女性抑郁症患者治疗前血清FT4,TSH较对照组低(P均<0.01),而FT3与对照组差异无显著性(P>0.05)。治疗后两组间差异无显著性(P>0.05)。

Objective：To explore the relationship between serum thyroid hormone levels and women＇s depression.Method：Serum triiodothyronine（FT3）,free thyroxin（FT4）and thyroid stimulating hormone（TSH） were tested using immuno-chemical luminescence in 58 female patients with depression before treatment and were compared to those in 40 healthy women.Results：Women with depression had lower serum FT4 and TSH levels than the healthy women（P0.01）,and no significant FT3 difference was found between the two groups before treatment（P0.05）.After treatment there were no significant differences in FT3,FT4 and TSH between the two groups（P0.05）.Conclusion：Female patients with depression show lower thyroid function than normal women.