代谢综合征对急性心肌梗死患者预后的影响

Impact of metabolic syndrome on the prognosis of patients with acute myocardial infarction

目的探讨代谢综合征(MS)对急性心肌梗死(AMI)预后的影响。方法将94例初发AMI患者分为AMI+MS组(43例)和AMI+非MS组(51例),比较2组患者心功能、左心室重构、心肌梗死后的心绞痛发作率和心性病死率。结果 AMI+MS组左心室舒张末期容积、左心室收缩末期容积和左心室舒张末期内径均较非MS组明显增加,左心室射血分数较AMI+非MS组明显减少。AMI+非MS组心肌梗死后的心绞痛发作率和心源性死亡率分别为17.6%和9.8%,AMI+MS组分别为34.8%和30.2%,两者比较差异有显著性。结论 AMI并有MS的患者左心室重构和心功能损害更明显,心肌梗死后的心绞痛发作率和心源性死亡的危险性增加。

【Objective】 To investigate the influence of metabolic syndrome（MS） on prognosis of AMI patients.【Methods】 Ninety-four patients with primary acute myocardial infarction were divided into two groups： AMI＋non-MS group and AMI＋MS group.Left ventricular remodeling and dysfunction and mortality and After myocardial infarction angina rate were compared between the two groups.【Result】 End-systolic left ventricular volume,end-diastolic left ventricular volume and end-diastolic left ventricular internal diameter were increased in metabolic syndrome groups compared with non metabolic syndrome group, left ventricular ejection fraction was decreased in metabolic syndrome groups compared with non metabolic syndrome group.A significantly different mortality and anginal attack rate were found between two groups.【Conclusion】 Metabolic syndrome could make left ventricular remodeling and dysfunction more notability in patients with acute myocardial infarction.The mortality and after myocardial infarction angina rate increased in acute myocardial infarction patients with metabolic syndrome.