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成分输血治疗剖宫产术中弥漫性血管内凝血的临床分析 被引量:8

Component blood transfusion in treatment of disseminated intravascular coagulation during cesarean section
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摘要 目的观察成分输血治疗剖宫产术中弥漫性血管内凝血(DIC)的疗效。方法参照DIC诊断标准、治疗原则及成分输血方案制订详细的孕产妇DIC治疗方案,在去除病因的基础上,A组输血内容以补充红细胞悬液、新鲜冰冻血浆及纤维蛋白原,临床纠正失血性休克、及时去除诱发DIC病因等综合治疗;B组输血内容在A组治疗的基础上补充单采血小板、冷沉淀,临床纠正失血性休克、及时去除诱发DIC病因等综合治疗。分析两组输血治疗前后凝血酶原时间(PT)、部分凝血活酶时间(APTT)、纤维蛋白原定量(FGB)、血小板计数(PLT)、凝血酶凝固时间(TT)、红细胞压积(HCT)和纤维蛋白降解产物D-二聚体(D-D)的变化及临床出血情况。结果两组患者治疗后血液学检查血红蛋白(HGB)、HCT、PLT、PT、APTT、D-D等指标与输血前比较均明显改善,差异有统计学意义(P<0.01或P<0.05)。B组的PT、TT、D-D指标结果改变优于A组,总出血量少于A组(P<0.05)。结论成分输血抢救孕产妇DIC出血有一定疗效,在去除病因后早期输注成分血、及时补充足量的凝血因子可消除其凝血障碍,对赢得抢救时间有积极作用。
出处 《第二军医大学学报》 CAS CSCD 北大核心 2011年第8期924-926,共3页 Academic Journal of Second Military Medical University
基金 上海市卫生局基金(2010155)~~
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参考文献13

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二级参考文献31

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