高血压左心室肥厚临床危害及治疗对策

Left ventricular hypertrophy in hypertension:hazards and treatment strategy

高血压左心室肥厚(LVH)的发生除与血压相关外还与生物力学、神经体液及遗传因素相关。循证医学证据表明,LVH是冠心病、心力衰竭、心脏猝死及脑卒中等心血管事件的独立危险因素。长期有效地降压治疗可以在很大程度上逆转LVH,并减少与之相关的心血管事件。

The pathogenesis of LVH is very complex,in addition to blood pressure,it related to biomechanics, neurohumoral and genetic factors. Based on evidence-based medicine：LVH are independent risk factor for coronary heart disease,heart failure,sudden cardiac death, stroke and other cardiovascular events. Long-term effective antihypertensive treatment can largely reverse the LVH,and reduce the associated cardiovascular events.