中药联合窄谱中波紫外线治疗寻常性银屑病伴代谢综合征的临床研究

Clinical Study of Traditional Chinese Medicine and NB-UVB on Psoriasis with Metabolic Syndrome

目的评价中药联合窄谱中波紫外线(NB-UVB)治疗银屑病伴代谢综合征(MS)的临床疗效及对血液流变学的影响。方法 120例银屑病伴代谢综合征的患者,分成光疗组、中药组和联合组,每组40例病人,疗程8周,治疗前后进行PASI评分判断疗效,检测血液流变学情况。结果联合组疗效优于中药组(P<0.05);联合组与光疗组的疗效无差异(P>0.05),但联合组治疗前后的血液黏度和血浆黏度明显降低(P<0.05,P<0.01)。结论中药联合NB-UVB治疗银屑病伴代谢综合征疗效明显,且能降低全血黏度和血浆黏度,改善微循环,有利于心脑血管疾病的防治。

Objective To investigate the clinical effect and influence of hemorheology of Chinese medicine and NB-UVB on psoriasis with metabolic syndrome（MS）.Methods 120 patients with psoriasis and MS were divided into three groups including phototherapy group,the Chinese medicine group and the combination group.There were 40 patients in each group.The course was eight weeks.The effect and hemorheology were evaluated by the PASI score before and after the treatment.Results There was significant difference between the combination group and Chinese medicine group（P0.05）.And no obvious difference was found between the combination group and phototherapy group（P0.05）.But the blood viscosity and plasma viscosity of the patients in combination group were obviously reduced after the treatment（P0.05,P0.01）.Conclusion The clinical effect of traditional Chinese medicine and NB-UVB was obvious.It could lower the blood viscosity and plasma viscosity,improve the microcirculation,and be beneficial to prevent and cure the heart cerebrovascular disease.