银屑病与代谢综合征关系的Meta分析

Meta-analysis on Correlation Between Psoriasis and Metabolic Syndrome

目的探讨银屑病（psoriasis）与代谢综合征（metabolic syndrome）之间的关系。方法检索有关银屑病与代谢综合征关系的文献,纳入符合标准的研究,应用Stata11.0软件进行Meta分析,比较银屑病组与对照组代谢综合征的发生率。结果纳入相关文献5篇,Meta分析显示银屑病组代谢综合征与缺血性心肌病的发生率均显著高于对照组,优势比OR分别为2.14（95%CI,1.54~2.98）和2.42（95%CI,1.19~4.92）,纳入研究不存在显著发表偏倚。结论银屑病患者中代谢综合征与缺血性心肌病的发生率高于对照。

Objective To demonstrate the correlation between psoriasis（PS） and metabolic syndrome.Methods Studies on the correlation between psoriasis and metabolic syndrome were searched,those achieved the criteria for inclusion was selected.Meta-analysis was performed using Stata11.0 software to compare the prevalence of metabolic syndrome with respect to psoriasis patients and controls.Results Five studies were included.Meta-analysis showed that metabolic syndrome and ischemic cardiomyopathy was more prevalent in psoriasis patients than in controls.The odds ratio（OR） was 2.14（95%CI,1.54~2.98）and 2.42（95%CI,1.19~4.92）respectively.No significant publication bias was found in the study.Conclusion Patients with psoriasis have a higher prevalence of metabolic syndrome and ischemic cardiomyopathy compared with controls.