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尤瑞克林治疗急性脑梗死的临床疗效观察 被引量:6

The clinical efficacy of urinary kallikrein in treatment of acute cerebral infarction
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摘要 目的探讨尤瑞克林对急性脑梗死的临床疗效及安全性。方法将急性发病(6~48 h)的脑梗死患者76例随机分为治疗组42例和对照组34例,分别评价NIHSS评分、ADL评分及NIHSS评分变化情况判定临床疗效,并观察不良反应。结果治疗组的临床疗效明显好于对照组,且无明显不良反应。结论 尤瑞克林治疗急性脑梗死安全有效。 Objective To observe the clinical efficacy and safety of urinary kallikrein on acute cerebral infarction.Methods 76 cases with the acute cerebral infarction within 6-48h were divided into treatment group(n=42) and control group(n=34).Each group was appraised the clinical efficacy by nerve function damage degree(NIHSS),daily life energy(ADL) and the change of the NIHSS and observed the adverse effects.Results The clinical efficacy of the treatment group was much better than that of the control group;moreover,there was no significant adverse effect in two groups.Conclusion It is safe and effective by using urinary kallikrein on acute cerebral infarction.
出处 《临床军医杂志》 CAS 2011年第4期650-652,共3页 Clinical Journal of Medical Officers
关键词 尤瑞克林 急性脑梗死 临床疗效 urinary kallikrein acute cerebral infarction clinical efficacy
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  • 1周毅,邹赛德,苏镇培,刘燕,胡珊,卢林.脑梗塞早期发病机制的系统分析研究[J].医学信息(医学与计算机应用),2003,16(9):474-476. 被引量:5
  • 2石秦东,张军峰,张蓬勃,王雪,陈新林,田玉梅,杨蓬勃,张建水,刘勇.尤瑞克林对大鼠局灶性脑缺血半暗带脑血流量影响的研究[J].中国神经精神疾病杂志,2008,34(7):413-416. 被引量:75
  • 3Wanger S, Kal BP, Lukosava M, et al. Activation of the tissue kall ikrein kinin system in stroke [ J ]. Neur Sciences, 2002,2 (5) :75 -76.
  • 4Perez V, Leiva-Salcedo E, Acuna-Castilloc, et al. Tkininogen in ducesces endothelial cell prolifleraion [ J ]. Mech Ageing Dev, 2006,12 ( 7 ) : 282 - 289.
  • 5Porcu PE, Manueli C, Kapatsoris M, et al. Reversal of angiogenic growth factor up regulation by revascularization of lower limb ischemia[ J]. Circulation ,2002,105:67 - 72.
  • 6龚浠平.尤瑞克林改善脑血管储备能力的研究[J].中国卒中杂志,2007,2(6):545-548. 被引量:77
  • 7Nagano H, Suzuki T, Nakamura S, et al. Pharmacological studies on human urinau kininogenase (SK-827):cerebral protetive effects[ J]. Yakugaku Zasshi, 1993,113 : 803 - 809.
  • 8Nagano H,Suzuki T,Tomoguri T,et al. Pharmacological studies on human ufinar, v kininogenase( SK-827 ) :effects on cerebral metabolism [ J ]. Yakugaku Zasshi, 1993,113 : 825 - 828.
  • 9Xia CF, Yin H, Borlongan CV, et al. Kallikrein gene transfer protects against isehemic stroke by promoting glial cell migration and inhibiting apoptosis [ J ]. Hypertension, 2004, 43 : 452 - 459.
  • 10Emanueli C, Graiani G, Salis MB, et al. Prophylactic gene therapy with human tissue kallikrein ameliorates limb ischemia recovery in type I diabetic mice [ J ]. Diabetes, 2004,53 : 1096 - 1113.

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