中晚期原发性肝癌96例肝动脉化疗栓塞的疗效分析

Efficacy analysis of TACE in 96 cases of advanced primary hepatocellular carcinoma

目的总结肝动脉化疗栓塞术(TACE)治疗中晚期肝癌的疗效。方法 96例无法切除的中晚期肝癌接受了1～7次TACE(平均1.7次),回顾性分析治疗效果和生存率。结果超选择性肝动脉插管成功率97.9%,1例术后1周因门脉高压突发食管胃底曲张静脉破裂大出血死亡,6个月、1、3年生存率分别为95.8%、72.9%和26%。结论 TACE联合其他抗癌治疗能有效地缓解中晚期肝癌症状和延长生存期。

Objective To summarize the efficacy of transarterial chemoembolization（TACE） in treating advanced hepatocellular carcinoma.Methods Ninety-six patients with unresectable hepatocellular carcinoma underwent 1～7 times（average 1.7 times） of TACE.The results were evaluated retrospectively and then analyzed the survival rate.Results Success rate of superselective hepatic artery catheterization was 97.9%.One patient died from bleeding of hepatic cirrhosis,portal hypertension combined with upper gastrointestinal hemorrhage.The survival rates of 6 months,1 year and 3 year were 95.8%,72.9% and 26% respectively.Conclusion Combination therapy of TACE with other anti-tumour methods can significantly increase survival rate in patients with unresectable primary hepatocellular carcinoma.