某部乙型病毒性肝炎感染现况调查

An investigation of hepatitis B infection in a certain army

目的调查某部乙型肝炎病毒(HBV)在新兵人群中的感染状况,为预防策略提供科学依据。方法根据分散选点、整群抽样的原则,确定某部的调查对象,通过专人询问并填写统一的流行病学调查表,采集调查对象静脉血3～5 ml,分离置于-20℃保存备用,统一采用SPRIA方法检测调查对象血清中HBsAg、抗-HBs、抗-HBc,ELISA方法检测调查对象血清中HBeAg、抗-HBe。结果所有受检人员HBsAg总阳性率为0.48%,抗HBs总阳性率为61.90%;城市新兵与农村新兵HBsAg总阳性率无统计学差异(P>0.05);不同年龄段的新兵HBsAg、抗HBs、抗HBe和(或)抗HBc阳性率差异无显著性(P>0.05)。结论 部队预防HBV,应同等对待不同入伍年限和兵源地的入伍新兵,有近40%的新兵抗HBs阴性,故有必要广泛对新兵进行乙肝疫苗接种。

Objective To investigate the unit of hepatitis B virus（HBV） infection in the population status of recruits,and to provide a scientific basis for prevention strategies.Methods Determine the unit＇s survey by a specialist inquiries and fill in unified epidemiological survey questionnaire,collect object venous blood 3-5ml,separate serum and save backup in-20℃.Using unified SPRIA method to detect respondents＇serum HBsAg,anti-HBs,anti-HBc,and to detect serum HBeAg,anti-Hbe by ELISA.Results Among all survey,the total ratios of HBsAg positive and anti-HBs positive were 0.48% and 61.90%;The difference of HBsAg positive rate between city recruits and rural recruits was not statistical（P0.05）;The difference of positive rate of HBsAg,anti-HBs,anti-Hbe and/or anti-HBc positive rate in different age were not statistical（P0.05）.Conclusion In order to prevent HBV,Army should coequal treat different ex-fighters attainment and the military recruit political.Nearly 40% of new recruits＇anti-HBs were negative,it is necessary for new recruits to widely inoculate HBV vaccine.