6[1]Hutchin T, Haworth I, Higashi K,et al. A molecular basis for human hypersensitivity to aminoglycoside antibiotics[J]. Nucleic Acids Res, 1993,21(18): 4174-4179.
7[2]Hutchin T. Sensorineural hearing loss and the 1 555 G mitochondrial DNA mutation[J]. Acta Otolaryngol,1999,119(1):48-52.
8[3]Guan MX, Fischel-Ghodsian N, Attardi G. Nuclear background determines biochemical phenotype in the deafness associated mitochondrial 12S rRNA mutation[J]. Hum Mol Genet,2001,10(6): 573-580.
9[4]Estivill X, Govea N, Barcelo E,et al. Familial progressive sensorineural deafness is mainly due to the mtDNA A 1 555 G mutation and is enhanced by treatment of aminoglycosides[J]. Am J Hum Genet, 1998,62(1): 27-35.
10[5]El-Schahawi M, Lopez de Munain A. Two large Spanish pedigrees with nonsyndromic sensorineural deafness and the mtDNA mutation at nt 1 555 in the 12 s rRNA gene: evidence of heteroplasmy[J]. Neurology, 1997,48(2): 453-456.
4Rybak MJ, Abate BJ, Kang SL, et al. Prospective evalu- ation of the elect of an aminoglycoside dosing regimen on rates of observed nephrotoxicity and ototoxicity[J]. Anti- microb Agents Chemother, 1999, 43(7): 1549.
