内科治疗胃食管反流临床分析

Clinical analysis of gastroesophageal reflux treated by medical treatment

目的:探讨内科治疗胃食管反流的临床效果。方法:选取广州军区总医院附属一五七医院近年收治的胃食管反流患者68例,随机分为对照组(34例)和治疗组(34例),对照组给予奥美拉唑+多潘立酮(吗丁啉)治疗,治疗组给予奥美拉唑+西沙必利治疗,比较两组症状、内镜评分及治疗效果。结果:两组患者治疗前症状及内镜评分比较,差异均无统计学意义(均P>0.05),治疗后治疗组与对照组综合评分分别为(6.6±2.2)、(12.0±3.6)分,两组比较,差异有高度统计学意义(P<0.01);治疗组显效31例,有效2例,有效率为97.06%,对照组显效25例,有效4例,有效率为85.29%,两组比较,差异有统计学意义(P<0.05)。结论:奥美拉唑联合全胃肠动力药,治疗效果优于联合胃动力药,临床效果满意,值得推广应用。

Objective：To discuss the clinical efficacy of the patients with gastroesophageal reflux treated by medical treatment.Methods：68 cases of the patients with gastroesophageal reflux were randomly divided into the control group（34 cases） and the treatment group（34 cases）.The control group were treated by Omeprazole combined with Domperidone,and the treatment group were treated by Omeprazole combined with Cisapride.And then the score of symptom and endoscopic and the clinical effect of the two groups were compared.Results：The score of symptom and endoscopic all had no significant difference before treatment（all P0.05）.The comprehensive score of the treatment group and the control group were（6.6±2.2） scores and（12.0±3.6） scores,there were significant differences between two groups（P0.01）.31 cases of the treatment group were marked effective,and 2 cases were effective,the effective rate was 97.06%.25 cases of the control group were marked effective,and 4 cases were effective,the effective rate was 85.29%,and there were significant differences between the two groups（P0.05）.Conclusion：The clinical effect of Omeprazole combined with Cisapride is superior to the Omeprazole combined with Domperidone.It is satisfactory,and is worth popularizing.