血必净合蒲公英外敷治疗急性蜂窝组织炎58例

Dandelion Combined Xuebijing Topical Treatment for Acute Cellulitis:A Report of 58 Cases

目的:观察血必净联合自制蒲公英软膏外敷治疗急性蜂窝组织炎的临床疗效。方法:将符合病例入选标准的116例患者随机分为治疗组、对照组各58例。两组均给予抗生素静脉滴注治疗。治疗组同时给予血必净静脉滴注及自制蒲公英软膏外敷。两组患者者均6 d为1个疗程,治疗1个疗程后观察疗效。结果:对照组治愈率为60.00%,总有效率为78.33%;治疗组治愈率为83.33%,总有效率为96.67%,治愈率、总有效率两组相比差异有统计学意义(P<0.05)。两组治疗前后临床症状积分及慢反应物质(CRP)、肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6),白细胞介素-8(IL-8)等检测指标均有明显改善(P<0.05);治疗组以上检测指标改善明显优于对照组(P<0.05)。结论:血必净联合自制蒲公英软膏外敷治疗急性蜂窝组织炎临床疗效显著,可较好的改善临床症状,调节炎症因子。

Objective：To observe clinical efficacy for treatment of acute cellulitis by the self-made dandelion combined Xuebijing topical ointment.Method： The inclusion criteria found 116 cases.The patients were randomly divided into two groups：control group and treatment group（58 cases,each）.Two groups were given intravenous antibiotic therapy.Treatment group was given Xuebijing intravenously with topically ointment of dandelion.After a course of 6 d treatment effects were observed.Result：The curative rate of control group was 60.00%,total effective rate was 78.33%;treatment group the curtive rate was 83.33%,total effective rate was 96.67%.Comparison of cure rate,the total effective in the 2 groups was significant（P0.05）.In the 2 groups,before and after treatment symptom scores,CRP,TNF-α,IL-6 and IL-8,showed statistically significant difference compared（P0.05）.The effect of the treatment group was better than that in the control（P0.05）.Conclusion：The dandelion combined Xuebijing topical ointment for treatment of acute cellulitis is effective significantly,the improvement of clinical symptoms is good with effect for regulation of inflammatory cytokines.