我院开展药物警戒工作的模式与经验探讨

Work Model and Experience Investigation of the Development of Pharmacovigilance in Our Hospital

目的:评价我院开展药物警戒工作的模式与经验。方法:介绍我院开展药物警戒工作的流程与模式。结果:我院通过对"有效预警信号"的提取、分析和研究,采取充分发挥药事管理与治疗委员会的作用,加强药品不良反应(ADR)监测网络建设,完善并扩大ADR的监测范围,本着"可疑即报"的原则,对用药期间出现的医疗事件进行监测,定期进行ADR信息反馈,将药品说明书嵌入医师工作站,对医、护、药、患者加强药学教育等药物警戒措施,结果取得了一定成效。结论:我院通过开展药物警戒工作,重视早期发现新的、严重的ADR,提高了安全用药水平。

OBJECTIVE： To evaluate the work model and experience of the development of pharmacovigilance in our hospital. METHODS： The work model and work flow of the development of pharmacovigilance in our hospital were introduced. RESULTS： By extracting, analyzing and researching ＂effective early warning signals＂, we played the role of pharmaceutical management and therapeutics committee, strengthened the adverse drug reaction （ADR） monitoring network and then perfected and extended the scope of ADR monitoring. Persisting in the principle of ＂to report every suspicious event＂, we monitored every medical event during the period of medication therapy. The information of ADR was fed back to the doctors and nurses regularly and the package inserts were appended to computerized prescription order entry （CPOE） by information technology. We iritensified pharmacy education among doctors, nurses, pharmacist and patients to achieve sound results. CONCLUSION： By developing pharmacovigilance in our hospital, we pay attention to find new and serious ADR early and improve the safety of drug use.