成都地区17家医院2007-2009年抗高血压药利用分析

Analysis of the Utilization of Antihypertensive Drugs in 17 Hospitals of Chengdu Area from 2007 to 2009

目的:了解成都地区医院抗高血压药的应用情况。方法:对成都地区17家医院抗高血压药的种类、销售金额、用药频度(DDDs)及日均费用等进行回顾性分析。结果:该地区医院抗高血压药的销售金额和DDDs逐年上升,销售金额排序列前10位的以钙拮抗药、血管紧张素受体Ⅱ抑制剂(ARB)、血管紧张素转换酶抑制剂(ACEI)为主。3年中,销售金额排序列第1位的均为氨氯地平;DDDs排序列前3位的药品有所变化,2009分别是氨氯地平、普萘洛尔、非洛地平。结论:成都地区医院抗高血压药以钙拮抗药、ARB和ACEI为主,钙拮抗药的销售金额占据了抗高血压药总销售额的近50%,ARB有望成为今后高血压的主要治疗药物。

OBJECTIVE： To investigate the utilization of antihypertensive drugs in Chengdu area. METHODS： The utilization of antihypertensive drugs in 17 hospitals of Chengdu area was analyzed retrospectively in respect of drug types, consumption sum, DDDs and DDC. RESULTS： The consumption sum and DDDs of antihypertensive drugs were increasing year by year. Top 10 drugs in the list of consumption sum were calcium channel blockers, ARB and ACEI. The first place of consumption sum was amlodipine in last 3 years. The top three drugs in the list of DDDs were amlodipine, propranolol and felodipine in 2009. CONCLUSION： The antihypertensive drugs in Chengdu area are predominated by calcium channel blockers, ARB and ACEI. The half consumption sum of drugs is occupied by calcium channel blockers. ARB will possibly become principal antihvpertensive druz.