摘要
目的:探讨药学服务对恶性肿瘤患者药物治疗安全性、依从性的影响。方法:随机将448例符合病例选择标准的患者分为试验组、对照组,各224例,均接受医护人员提供的医疗服务;试验组患者及其家属、相关医护人员同时接受临床药师提供的至少3个月药学服务。结果:试验组患者治疗依从性较对照组明显升高(P<0.05);出现严重不良反应的构成比较对照组低,但差异无统计学意义(P>0.05)。结论:药学服务可以降低抗肿瘤药致严重不良反应的发生率,明显提高患者治疗依从性。
OBJECTIVE: To investigate the effect of pharmaceutical care on the safety of drug therapy and the compliance of patients with malignant tumor. METHODS: 448 cases who met the selection criteria were randomly divided into the trial group and control group (n=224). Both groups accepted medical services. Meanwhile, the patients and their family and the related medical staffs in the trial group accepted the pharmaceutical care for at least 3 months by clinical pharmacists. RESULTS: Compliance of patients in the trail group was significantly increased as compared with control group (P〈0.05) ; while constituent ratio of patients suffering from serious adverse drug reactions in the trail group was lower than in the control groups, but there was no statistical significance (P〉0.05). CONCLUSIONS: Pharmaceutical care can reduce the incidence of the serious adverse drug reactions induced by antineoplastic drugs, and improve the compliance of the patients obviously.
出处
《中国药房》
CAS
CSCD
北大核心
2011年第34期3239-3241,共3页
China Pharmacy
基金
山东省药学会临床药学奥赛康中青年科研资助项目(P200903)
关键词
药学服务
临床药师
恶性肿瘤
安全性
依从性
Pharmaceutical care
Clinical pharmacist
Malignant
rnor
Safety
Compliance