实验动物肺癌模型的建立方法

Establishment of experimental animal models of lung cancer

建立肺癌的动物模型是肺癌研究的最常用的方法之一，但肺癌动物模型与人类肺癌的结果一直存在差距，很多研究人员一直在试图建立与人类肺癌最为接近的动物肺癌模型。根据制备方法及研究目的的不同，肺癌动物模型可分为自发性、诱发性、移植性和基因改造型动物模型。每种肺癌动物模型的制作方法是一个肺癌模型评定的重要方面之一。

Establishment of animal models of lung cancer is one of the most commonly used methods in lung cancer research,but there is a wedge between animal models of lung cancer and patients with lung cancer. Many researchers are trying to establish the animal models of lung cancer which is the proximate to human lung cancer. According to the method and destination, the animal models of lung cancer include spontaneous, induced, transplanted and genetically modified models. The method of establishment is one of the most crucial aspects of assessing lung cancer models.