1Wald NJ,Rodeck C,Hackshaw AK,et al.First and second trimester ante - natal screening for Down's syndrome:the resuits of the serum,urine and ultrasound screening study(SU- RUSS). Health Technol Assess, 2003, 7( 11 ) : 1-77.
2Ball RH,Caughey AB,Malone FD,et al. First- and secondtrimester evaluation of risk for Down syndrome. Obstet Gynecol, 2007, 110( 1 ) : 10-17.
4Cicero S,Curcio P,Papageorghiou A,et al.Absence of nasal bone in fetuses with trisomy 21 at 11-14 weeks gestation:an observational study.Lancet, 2001,358 : 1665-1667.
5Nyberg DA, Souter VL.Use of genetic sonography for adjusting the risk for fetal Down syndrome.Semin Perinatol, 2003,27 (2): 130-144.
6Lee MH, Ryu HM, Kim DJ, et al. Rapid prenatal diagnosis of Down syndrome using quantitative fluorescent PCR in uncultured amniocytes. J Korean Med Sci, 2004, 19(3):341-344.
7Cirigliano V, Voglino G, Cafladas MP,et al. Rapid prenatal diagnosis of common chromosome aneuploidies by QF-PCR: Assessment on 18,000 consecutive clinical samples. Mol Hum Reprod, 2004, 10( 11 ) : 839-846.
8Mann K ,Donaghue C ,Fox SP, et al. Strategies for the rapid prenatal diagnosis of chromosome aneuploidy. Eur J Hum Genet, 2004, 12( 11 ):907-915.
9Huhen MA,Jonasson J,Nordgren A,et al. Germinal and somatic trisomy 21 Mosaicism: how common is it, what are the implications for individual carriers and how does it come about? Curr Genomics, 2010, 11(6):409-419.
10Lee J,Stanley JR, Vaz SA,et al. Down syndrome with pure partial trisomy 21q22 due to paternal insertion (4;21) uncovered by uncultured amniotic fluid interphase FISH. Am J Med Genet A, 2005, 132(2) : 206-208.
9Wald NJ.Prenatal screening for open neural tube defects and Down syndrome: three decades of progress[J].Prenat Diagn,2010,30(7):619-621.
10Nakata N,Wang Y,Bhatt S.Trends in prenatal screening and diagnostic testing among women referred for advanced maternal age[J].Prenat Diagn,2010,30(3): 198-206.
