摘要
以邻氨基苯甲酸类化合物和醋酸脒为原料,经环合反应得到喹唑啉-4(3H)-酮类化合物,再经POCl3氯化后得到4-氯喹唑啉类化合物。所得化合物的结构均经核磁和质谱确证。
Quinazolin-4 (3H)-ones were conveniently synthesized from anthranilie acids and amidines via cyclization reaction, which could be chloridized with POCl3 to obtain 4-chloroquinazoline derivatives. The structures of the products were characterized by 1HNMR and MS.
出处
《浙江化工》
CAS
2011年第8期4-6,9,共4页
Zhejiang Chemical Industry
基金
国家自然科学基金资助项目(20876149)