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SALL4在疾病中的研究进展 被引量：4

Research Advances of SALL4 in Disease
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摘要 人类婆罗双树样基因-4(SALL4)是一种新发现的原癌基因,对维持胚胎干细胞的多能性和自我更新具有重要作用,其突变、过表达及调控与一些疾病的发生发展有关,现就SALL4的分子结构、生物学功能、作用机制及其与各种疾病的关系进行综述。 SALL4 which is essential for pluripotency and self - renewal of embryonic stem cells is a novel proto - oncogene. Genetic mutations, overexpression and regulation of SALIA may breed some diseases. This article reviews the molecular structure, biological functions and mechanisms of SALL4, and the relationship of SALL4 and diseases.
作者 卜建设 李宝艳 秦成路 廖莳
机构地区 广东医学院研究生院 深圳市罗湖区人民医院
出处 《中外医学研究》 2011年第24期157-159,共3页 CHINESE AND FOREIGN MEDICAL RESEARCH
关键词 SALL4 原癌基因 肿瘤 SALL4 Proto - oncogene Tumour
分类号 R730.2 [医药卫生—肿瘤]
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参考文献4

二级参考文献50

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共引文献21

同被引文献34

  • 1滕梁红,卢德宏,徐庆中,付永娟,杨虹,贺志立.OCT4、CD117、CD30在生殖细胞肿瘤中的表达及鉴别诊断意义[J].中华病理学杂志,2005,34(11):711-715. 被引量：27
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中外医学研究
2011年 第24期

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