摘要
目的:比较胺碘酮与利多卡因治疗急性心肌梗死后室性心律失常的疗效。方法:将92例患者随机分为两组。利多卡因组以利多卡因50mg静注,必要时15min后重复一次至利多卡因总量达150mg,继以1~3mg/min的速度静脉滴注,维持24h。胺碘酮组以胺碘酮150mg于10min内静注,然后以1mg/min静脉滴注6h,再以0.05mg/min维持静滴至稳定后24h。分别判定疗效。结果:胺碘酮与利多卡因组急性心肌梗死后室性心律失常有效率分别为78.2%与60.9%,胺碘酮组的疗效明显高于利多卡因组,差别有统计学意义(P<0.05)。胺碘酮组病死率明显低于利多卡因组,差别有统计学意义(P<0.05)。结论:与利多卡因相比,胺碘酮静脉给药治疗急性心肌梗死后室性心律失常,能增加有效率,减少病死率。
Objective:To evaluare the efficacy of Amiodarone and Lidocaine on ventricular arrhythmias after acute myocardial infarction.Methods:92 example patients divide into two groups stochastically.Lidocaine group by Lidocaine 50mg static note,when necessity after 15min,is redundant one time reaches 150mg to the Lidocaine total quantity,the followed by 1~3mg/min speed vein drop note,maintains 24h.Amiodarone group by Amiodarone 150mg in 10min static note,then vein drop pours 6h by 1mg/the min,again maintains the static drop by 0.05mg/min after the stability 24h.Distinction determination curative effect.Results:Amiodarone and the Lidocaine level to the ventricular arrhythmias after acute myocardial infarction effectiveness respectively are 78.2% and 60.9%,Amiodarone group′s curative effect obvious high than Lidocaine group’s,has statistics significance(P〈0.05).The Amiodarone group′s mortality rate is lower than the Lidocaine group′s obviously,has statistics significance(P〈0.05).Conclusion:Amiodarone vein for the medicine treatment ventricular arrhythmias after acute myocardial infarction,can increase effectiveness,reduces the mortality rate.
出处
《中国民康医学》
2011年第16期1963-1963,1980,共2页
Medical Journal of Chinese People’s Health
关键词
胺碘酮
利多卡因
心肌梗死
心律失常
Amiodarone
Lidocaine
Myocardial infarction
Arrhythmia