单次热水足浴对健康青年动脉硬度的短时影响

Immediate effects of a single hot footbath on arterial stiffness in healthy young humans

目的:观察单次热水足浴对健康青年动脉硬度的短时影响。方法:应用均衡随机交叉自身对照设计,8名健康青年随机进入对照日和足浴日实验,均分别于三个时间点,即0 min、30 min和50 min重复测量其心-踝血管指数(CAVI),其中对照日实验中对受试者不进行任何干预,而足浴日实验中在0 min和30 min之间进行足浴,足浴的水温为42～45℃、持续30 min,7 d后每位受试者实验内容进行交叉。结果:对照日的三个时间点上,受试者的CAVI基本保持不变,分别为(6.3±0.9)、(6.3±0.8)和(6.5±0.8)。而足浴日中,CAVI基础值从(6.1±0.4)下降到30 min时的(5.4±0.5),P<0.01,和50 min的(5.7±0.4),P<0.05,差异具有显著性,30 min的CAVI显著低于对照日的30 min CAVI(P<0.05);而鼓膜温度在足浴后即刻也明显短暂升高。结论:单次足浴可使人体动脉硬度短时下降,这可能与核心体温的升高有关。

Objective：To observe immediate effects of a single hot footbath on arterial stiffness in human.Methods：With a counterbalanced,randomized crossover own control design,eight healthy young humans randomly entered trials of control or footbath days.Cardio-ankle vascular index（CAVI） was measured in the eight healthy young humans at 0 min（baseline）,30 min and 50 min.Subjects in control trial received no intervention while those in footbath trial underwent footbath at 42～45℃ for 30 min.After seven days,trial extent of each subject was crossed.Results：At the three time points in control trial,CAVI of the subjects were（6.3±0.9）,（6.3±0.8） and（6.5±0.8） respectively,which kept constant on the whole.But in footbath trial,baseline CAVI（6.1±0.4） decreased to（5.4±0.5）,P〈0.01,at 30 min and（5.7±0.4）,P〈0.05,at 50 min,and there existed significant difference on CAVI at 30 min compared with that of control day（P〈0.05）.Tympanic temperature also significantly increased immediately after footbath.Conclusion：A single footbath could improve arterial stiffness in human for a short period,and it may be associated with elevated core temperature.