摘要
在其它HPLC分析条件不变的前提下,本实验考察了地西泮、艾司唑仑、氯氮卓、三唑仑4种苯二氮卓类药物保留时间、拖尾因子、峰面积3个指标随流动相水相PH值改变而变化的趋势,初步总结了流动相pH值对4种药物HPLC色谱行为的影响。
Fixing other parameters,the change of the diazepam,Estazolam,Chlordiazepoxide and triazolam in retention time,tailing factor and peak area with PH value were studied in reversed phase high performance liquid chromatography.And the impact of PH value on the chromatography behavior of the four drugs was summarized preliminarily.
出处
《化学工程师》
CAS
2011年第8期26-28,共3页
Chemical Engineer
基金
基本科研业务费专项资金重点项目(2009JBGG001)
关键词
地西泮
艾司唑仑
氯氮卓
三唑仑
流动相pH值
HPLC色谱行为
diazepam
estazolam
chlordiazepoxide
triazolam
pH value of liquid phase
HPLC chromatography behavior
