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甲氨喋呤与米非司酮联合治疗异位妊娠65例疗效观察 被引量:5

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摘要 目的:观察甲氨喋呤与米非司酮联合治疗异位妊娠的疗效。方法:选择2008年12月-2010年3月收治的130例异位妊娠患者行保守治疗,随机分为两组,观察组给予甲氨喋呤20 mg肌内注射,1次/d,联合口服米非司酮50 mg,2次/d,共5 d;对照组甲氨喋呤50 mg肌内注射,隔天1次,共5次。结果:观察组疗效明显优于对照组(P〈0.01),观察组血β-HCG下降至正常范围所需时间及盆腔包块缩小时间均较对照组短,两组比较差异有统计学意义(P〈0.05),观察组不良反应发生率明显低于对照组(P〈0.05)。结论:甲氨喋呤与米非司酮联合治疗异位妊娠疗效显著、见效快、不良反应少,值得推广。
作者 戴阿莉
出处 《吉林医学》 CAS 2011年第23期4775-4776,共2页 Jilin Medical Journal
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