1DINH T,VEVES A.Microcirculation of the diabetic foot[J].Curr Pharm Des,2005,11(18):2301-2309.
2ARMSTRONG D G,LIPSKY B A.Diabetic foot infections:stepwise medical and surgical management[J].Int Wound J,2004,1(2):123-132.
3HUNT D.Diabetes:foot ulcers and amputations[J].Am Fam Physician,2009,80(8):789.
4TAYLOR E,COGDELL D,COOMBES K,et al.Sequence verification as quality-control step for production of cDNA microarrays[J].Biotechniques,2001,31(1):62-65.
7BRADY J,HAYAKAWA Y,SMYTH M J,et al.IL-21 induces the functional maturation of murine NK cells[J].J Immunol,2004,172(4):2048-2058.
8CAUDELL E G,MUMM J B,POINDEXTER N,et al.The protein product of the tumor suppressor gene,melanoma differentiation-associated gene 7,exhibits immunostimulatory activity and is designated IL-24[J].J Immunol,2002,168(12):6041-6046.
9SIEGER K A,MHASHILKAR A M,STEWART A,et al.The tumor suppressor activity of MDA-7/IL-24 is mediated by intracellular protein expression in NSCLC cells[J].Mol Ther,2004,9(3):355-367.
二级参考文献20
1[1]Habib T,Senadheera S,Weinberg K,et al.The common gamma chain (γc) is a required signaling component of the IL-21 receptor and supports IL-21-induced cell proliferation via JAK3[J].Biochemistry,2002,41(27):8725-8731.
2[2]Parrish-Novak J,Dillon SR,Nelson A,et al.Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function[J].Nature,2000,408(6808):57-63.
3[3]Wurster AL,Rodgers VL,Satoskar AR,et al.Interleukin 21 is a T helper (TH) cell 2 cytokine that specifically inhibits the differentiation of naive TH cells into interferon γ-producing TH1 cells[J].J Exp Med,2002,196(7):969-977.
4[4]Coquet JM,Kyparissoudis K,Pellicci DG,et al.IL-21 is produced by NKT cells and modulates NKT cell activation and cytokine production[J].J Immunol,2007,178(5):2827-2834.
5[5]Ozaki K,Kikly K,Michalovich D,et al.Cloning of a type I cytokine receptor most related to the IL-2 receptor beta chain[J].Proc Natl Acad Sci USA,2000,97(21):11439-11444.
6[6]Strengell M,Sareneva T,Foster D,et al.IL-21 up-regulates the expression of genes associated with innate immunity and TH1 response[J].J Immunol,2002,169(7):3600-3605.
7[7]Strengell M,Matikainen S,Siren J,et al.IL-21 in synergy with IL-15 or IL-18 enhances IFN-γ production in human NK and T cells[J].J Immunol,2003,170(11):5464-5469.
8[8]Zeng R,Spolski R,Casas E,et al.The molecular basis of IL-21-mediated proliferation[J].Blood,2007,109(10):4135-4142.
9[9]Mehta DS,Wurster AL,Whitters MJ,et al.IL-21 induces the apoptosis of resting and activated primary B cells[J].J Immunol,2003,170(8):4111-4118.
