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ω-3鱼油脂肪乳对消化系统肿瘤患者T淋巴细胞亚群的影响 被引量:6

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摘要 目的探讨消化系统肿瘤患者外周血中T淋巴细胞亚群在使用ω-3鱼油脂肪乳前后的变化及其可能机制。方法 38例消化系统肿瘤患者分为常规全胃肠外营养(TPN)组(A组)和鱼油脂肪乳+TPN组(B组),分别检测两组患者在治疗前及治疗第3、7天时外周血T细胞亚群的比例及TBIL、AST、ALT水平。结果 B组在使用ω-3鱼油脂肪乳7 d时CD3+、CD4+、CD8+细胞较治疗前有所上升,3 d时与A组差异无统计学意义;CD8+CD28+细胞在治疗3 d时较治疗前升高,治疗7 d时较使用前差异无统计学意义。A组在各个时间点变化不明显。两组AST、ALT较治疗前有所上升,但B组的AST、ALT与A组相比有所下降。NK、CD4+CD45RA、CD8+CD28-、TBIL在两组间和各个治疗时间点差异无统计学意义。结论ω-3鱼油脂肪乳能改善患者细胞免疫功能,增强机体抗肿瘤的能力,并可改善肝功能,有利于促进患者的康复。
出处 《广东医学》 CAS CSCD 北大核心 2011年第16期2085-2087,共3页 Guangdong Medical Journal
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