动态血糖监测系统联合胰岛素泵在糖尿病患者围手术期的临床应用

The clinical uses of dynamic blood sugar monitoring system combine with insulin pump for perioperative diabetic

目的评价动态血糖监测系统及胰岛素泵在糖尿病患者围手术期治疗中的指导作用。方法选取120例围手术期的2型糖尿病患者,随机分为3组:双C组(A组)、单纯CSⅡ组(B组),MDI组(C组)每日多次注射胰岛素组。双C组行CGMS连续监测血糖,后两组均采用指尖血糖仪监测血糖,分别根据各自的血糖监测结果调整治疗方案。各组强化治疗2周。结果①糖尿病患者围手术期使用双C组及CSⅡ手术切口愈合及防止切口感染明显优于MDI组;②空腹血糖:强化治疗后3组均明显下降,组内差异均有统计学意义(P<0.05),组间差异无统计意义(P>0.05)。③餐后2h血糖:强化治疗后3组均明显下降(P<0.05),双C组下降更明显(P<0.05),CSⅡ组与MDI组相较差异不明显;④血糖漂移:双C组MAGE显著低于CSⅡ及MDI(P<0.05),后两组差异无统计学意义(P>0.05);血糖达标时间双C组和CSⅡ组明显短于MDI组(P<0.05),差异有统计学意义(P<0.01)。

Objective To evaluate the effect of The Dynamic blood sugar monitoring system combine with insulin pump for perioperative diabetic.Methods 120 patients with diabetes II were divided into three groups.Group A use dynamic blood sugar monitoring system combine with insulin pump,group B use insulin pump,group C inject insulin several times every day.Both group B and C adjusted the treatment according to the blood sugar monitored by Fingertip blood glucose meter.All three group accepted two weeks intensive therapy.Results ①group A and B were better than group C in Postoperative wound healing and prevention of wound infection.②For three groups fasting blood glucose and two-hour postprandial blood glucose were statistically decreased after intensive therapy（P0.05）.Among three groups there weren＇t statistically difference in fasting blood sugar decrease（P0.05）.③The two-hour postprandial blood glucose and Blood glucose excursion in Group A were statistically decreased compare with group B and C（P0.05）,but no statistically difference between group B and C（P0.05）.④The time of blood sugar reaching the standard in group A and B were statistically lower than group C（P0.01）.Conclusion For perioperative diabetic the Dynamic blood sugar monitoring system combine with insulin pump were better to control blood sugar.