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核因子-κB在颅内动脉瘤发病中的作用 被引量:3

Effect of nuclear factor-κappa B on pathogenesis of intracranial aneurysm
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摘要 核因子-κB(NF-κB)是研究最为广泛的转录因子之一,在机体的免疫应答、炎症反应及细胞的生长调控等方面发挥着重要作用。NF-κB活化后可通过诱发局部动脉血管壁慢性炎症反应的形成,导致血管壁的破坏,从而诱导颅内动脉瘤的形成和发展。本文就NF-κB介导的炎症反应在颅内动脉瘤发病中的作用做一综述。
出处 《实用医院临床杂志》 2011年第5期185-188,共4页 Practical Journal of Clinical Medicine
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参考文献31

  • 1朱刚,陈志,缪洪平,王宪荣.颅内动脉瘤外科治疗及研究进展[J].实用医院临床杂志,2008,5(2):10-12. 被引量:3
  • 2Karin M, Yamamoto Y, Wang QM. The IKK NF-kappa B system: a treasure trove for drug development [ J ]. Nat Rev Drug Discov, 2004,3(1) : 17-26.
  • 3Iwai K, Lee BR, Hashiguchi M, et al. IkB-alpha-specific transcript regulation by the C-terminal end of c-Rd[ J]. FEBS Lett ,2005, 579 ( 1 ) : 141-144.
  • 4Liou HC. Regulation of the immune system by NF-kappaB and IkappaB [ J]. J Biochem Mol Biol,2002,35 (6) :537-546.
  • 5Li X,Massa PE, Hanidu A, et al. IKKalpha, IKKbeta, and NEMO/ IKK gamma are each required for the NF-kappa B -mediated inflammatory response program [ J ]. J Biol Chem, 2002,277 ( 47 ) : 45129- 45140.
  • 6Prendes M, Zheng Y, Beg AA. Regulation of develop ingB cell survival by RelA2containing NF2kappa B complexes [ J]. J Immunol, 2003, 171 (8) : 3963-3969.
  • 7Djavaheri-Merguy M,Amelotti M, Mathieu J, et al. NF-kappaB activation represses tumor necrosis factor-alpha-induced autophagy [ J ], J Biol Chem, 2006, 281 (41) : 30373-30382.
  • 8石翠格,胡刚,汪海.NF-κB在动脉粥样硬化中的始动作用[J].中国药理学通报,2004,20(4):382-385. 被引量:26
  • 9Li Qiu-tang, Inder MV. NF-KB regulation in the immune system [ J]. Nature Reviews Immunology,2002,2(2) :725-734.
  • 10Cathcart MK. Regulation of superoxide anion production by NADPH oxidase in monocytes/macrophages contributions to atherosclerosis [J]. Arterioscler Thromb Vasc Biol,2004,24( 1 ) :23-28.

二级参考文献80

  • 1赵继宗,王忠诚,孙异临,王硕,高鲜红,赵通印,曲宝清.颅内囊性动脉瘤临床病理研究[J].中华神经外科杂志,1996,12(4):234-237. 被引量:6
  • 2李明昌,石忠松,夏之柏,黄正松.国人颅内动脉瘤基因表达谱的初步研究[J].中国神经精神疾病杂志,2005,31(1):16-16. 被引量:6
  • 3赵明光,王晨,高永中,浦佩玉,宋振全,范涤,魏学忠.颅内囊性动脉瘤VEGF表达与瘤壁超微结构变化[J].中国神经精神疾病杂志,2005,31(2):130-131. 被引量:3
  • 4朱刚,陈志,缪洪平,王宪荣.血管内栓塞治疗颅内动脉瘤及其并发症的防治[J].第三军医大学学报,2005,27(17):1782-1784. 被引量:23
  • 5孙晓枫,乔桂荣,兰海涛,张庆俊.肾性高血压大鼠脑动脉瘤形成过程中NF-kB和MMPs表达的关系[J].中华神经外科杂志,2006,22(10):628-632. 被引量:14
  • 6[1]Rupp J,Koch M,vanZandbergen G,et al.Transmission of Chlamydia pneumoniae infection from blood monocytes to vascular cells in a novel transendothelial migration model[J].FEMS Microbiol Lett,2005,242 (2):203-208.
  • 7[2]May A.E,Redeeke V,Groner S,et al.Recruitment of Chlamydia pneumoniae-infected maerophages to the carotid artery wall in noninfected,nonatherosclerotic mice[J].Arterioscler-Thromb-Vasc-Biol,2003,23(5):789-794.
  • 8[3]Molyneux AJ,Kerr RS,Yu LM,et al.International subarachnoid aneurysm trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms:a randomised comparison of effects on survival,dependency,seizures,rebleeding,sub groups,and aneurysm occlusion[J].Lancet,2005,366 (9488):783-785.
  • 9[4]Raabe A,Beck J,Gerlach R,et al.Near-infrared indocyanine green video angiography:a new method for intraoperative assessment of vascular flow[J].Neurosurgery,2003,52(1):132-139.
  • 10[5]Woitzik J,Horn P,Vajkoczy P,et al.Intraoperative control of extracranial intracranial bypass patency by near-infrared indocyanine green videoangiography[J].Journal Of Neurosurgery,2005,102(4):692-698.

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