脑卒中相关性感染与预后关系探讨

Research on the relationship between stroke-associated infection and prognosis in patients with cerebral stroke

目的探讨脑卒中相关性感染(SAI)与脑卒中预后的关系。方法采用回顾性调查方法,分析762例经头颅CT/MRI证实且排除发病前感染征象的脑卒中患者的临床资料,调查SAI发病率,分析SAI发生的相关危险因素及SAI与脑卒中预后关系。结果 SAI发生率18.2%(139/762),SAI发生与患者老年合并糖尿病、意识障碍、吞咽困难、侵袭性操作密切相关,SAI组改良Rankin氏评分预后不良例数及住院天数两项指标均明显高于无合并SAI组。结论 SAI发生与多种危险因素相关,临床上应加以重视,采取综合治疗措施,提高免疫力,控制感染,改善脑卒中患者预后。

Objective To study the relationship between stroke-associated infection（SAI） and the prognosis of stroke.Methods A retrospective survey was performed in 762 cases of stroke confirmed through head CT/MRI and excluded signs of infection prior to the onset of stroke.The incidence of SAI was investigated,with a analysis of risk factors and the prognosis of patients with SAI.Results The incidence of SAI was 18.2%（139/762）,and SAI was closely related with senility,diabetes mellitus,consciousness disorders,swallowing difficulties and invasive operations.The numbers of poor prognosis evaluated with modified Rankin scores and the hospitalization days of SAI group were both significantly higher than those of non-SAI group.Conclusion SAI is related with a variety of risk factors.Comprehensive measures should be performed to improve immunity and control infection,and improve the prognosis of patients with stroke.