H5N1Re-5株和H9亚型SS株对土三黄鸡的免疫效果对比

Comparison on Immune Efficacy of Avian Influenza Virus Re-5 Strain and SS Strain in Guangxi Sanhuang Chickens

[目的]探究H5N1Re-5株和H9亚型SS株对土三黄鸡不同的免疫效果。[方法]选用广西桂林市某种鸡场土三黄鸡180只,试验组注射禽流感H5和H9疫苗,对照组不注射疫苗,检测145日龄注射H5和H9疫苗后的抗体水平。[结果]禽流感H5疫苗145日龄注射后第170日龄抗体检测:试验1、2组分别比各自对照组的平均抗体值比较差异达0.01极显著水平;禽流感H9疫苗145日龄注射后第170日龄抗体检测:试验1、2组分别比各自对照组的平均抗体值比较差异不显著。[结论]禽流感H5疫苗145日龄注射后能显著地提高抗体水平;禽流感H9疫苗145日龄注射后不能显著地提高抗体水平。

[Objective]To compare immune efficacy of avian influenza virus（AIV） Re-5 strain（H5N1 subtype） and SS strain（H9 subtype） in Guangxi Sanhuang chickens.[Method]oA total of 180 Sanhuang chickens were selected from a breeding chicken farm in Guilin City of Guangxi and assigned into four groups（n = 45）.At 145 days old,the chickens in the group I and II were inoculated with AIV Re-5 strain and AIV SS strain,but they were kept in cages separately.The two control groups were not inoculated.Antibody levels were determined at 170 days old.[Result]The level of antibodies against AIV Re-5 strain was significantly higher in the chickens of the group I and group II than in the corresponding control groups,respectively（P 0.01）.The level of antibodies against AIV SS strain was not significantly different between the group I and its control group or between the group II and its control group.[Conclusion]The antibody level of chickens can be increased by the AIV Re-5 strain but not by the AIV SS strain.