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瘦素与代谢综合征 被引量:3

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摘要 瘦素是脂肪组织分泌的细胞因子,通过与特异性受体的结合而发挥其生物学效应。有资料证实,瘦素不仅与肥胖密切相关,而且与微血管和大血管病变发生的一系列危险因素中的高血压、糖和脂质代谢紊乱等引起的代谢综合症密切相关。研究瘦素与代谢综合症的关系,对预防心脑血管病的发生、发展具有重要的意义。
出处 《检验医学教育》 2011年第2期39-41,共3页
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参考文献12

  • 1张刚,祝之明,赵志钢,倪银星,陈雪梅,张芸.代谢综合征危险因素的特征[J].高血压杂志,2004,12(1):83-86. 被引量:71
  • 2Krempler F,Breban D, Oberkofler H, et al. Leptin peroxisome activited receptorgamma, and CCAAT/enhancer binding pro tein alpha mRNA expression in adipose tissue of humans and their relation to cardiovascular risk factor [J]. Arterioscler Thromb Vasc Biol,2000,20(2) :443 449.
  • 3顾卫琼,陈名道,唐金凤,李凤英,陈春荣,罗敏,陈家伦,许曼音.中国人血清瘦素水平与肥胖度的关系[J].中华内分泌代谢杂志,1999,15(1):15-18. 被引量:193
  • 4Asakawa H, Tokunaga K, Kawakami F. Relationship of leptin level with metabolic disorders and hypertention in Japanese type 2 diabetes mellitus patiens[J]. J Diabeters and Its Compli- cations,2001,15(1) :57 62.
  • 5Fruenhwald Schultes B, Kren W, Beuer J, et al. Elevated ser um leptin concentrations in type 2 diabetic patients with mi croalbu-minuria and macroalbuminuria[J]. Metabolism, 1999 48.1290- 1293.
  • 6Ckaya G,Ozata M,Bauraktar Z,et al. Is leptin associated with diabetic retinopathy? [J]. Diabetes Care, 2000,23 .371-376.
  • 7Stangl K,Cascorbi I, Lanle M,et al. Elevated serum ieptin in patients with coronary diseaseno association with the Trp 64 Arg polymorphism of the beta 3-adrenergic receptor[J]. Int J Obes Relat Metab Disord,2000,24(3)369-375.
  • 8Serberg S,Ahr B,Jansson JH,et al. Leptin is associated with increased risk of myocardial infarction [J]. J Interm Med, 1999,246(4) :409- 418.
  • 9陈忠,马根山,黄峻,朱铁兵,杨志健,王连生,曹克将.瘦素与男性早发冠心病临床表型关系的初步探讨[J].中国急救医学,2003,23(5):310-311. 被引量:8
  • 10Wallace AM,Me Mahon AD,Chris JP,et al. Plasma leptin at the risk of cardiovascular disease in the West of Scotland Cor onary Prevention Study (WOSCPS) [J]. Circulation, 2001, 104:3052-3056.

二级参考文献43

  • 1贾伟平,项坤三,丁炜,陆俊茜.男性中国人体脂分布与激素模式[J].中华内分泌代谢杂志,1998,14(2):78-81. 被引量:20
  • 2Sinha MK,Caro JF.Clinical aspects of leptin[J].Vitamins & Hormones.1998.54:1-30.
  • 3SoderbergS,Ahren B,Jansson JH,etal.Leptinon is associated with increased risk of myocardial infarction[J].J Intern Med,1999,246:409-418.
  • 4Eckel RH,for the nutrition committee:obesity and heart disease.A statement for healthcare professionals from the nutrition committee,American Heart Association[J].Circulation,1997,96:3248-3250.
  • 5Suwaidi JA,WrightRS,Grill J,et al.Obesity is associated with premature occurrence of acute myocardial infarction[J].Clin Cardiol,2001,24:542-547.
  • 6Wallace AM,McMahon AD,Chris JP.et al.Plasma leptin at the risk of cardiovascular disease in the West of Scotland Coronary Prevention Study(WOSCPS)[J].Circulation,2001.104:3052-3056.
  • 7Wallace AM.Sattar N.McMillan DC.The coordinated cytokine/hormone response to acute injury incorporates leptin[J].Cytokine,2000,12:1042-1045.
  • 8Mohamed-Ali V,Pinkney JH,Coppack SW.Adipose tissue as an nendocrine and paracrine organ[J].Int J Obes,1998,22:1145-1158.
  • 9Couillard C,Lamarche B,Mauriege P,et al.Leptinemia is not a risk factor for ischemic heart disease in men:prospective results from the Quebec Cardiovascular Study[J].Diabetes Care,1998,21:782-786.
  • 10Houseknecht KL,Baile CA,Matteri RL,et al.The biology of leptin:a review[J].J Animal Sci,1998,76:1405-1420.

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